Danu being eye(Cerf) checked

Danu's Misdiagnosis

After 8 long years, Wildheart Danu at Storyteller, known as Danu, has finally been diagnosed,
with the right diagnosed, of her eye condition in November 2010.
I have seen several different eye specialist, over the last 8 years, who all felt the same about
Danu's eyes. Danu has been misdiagnosed as having suspicious pra, that would
turn into generalized pra.
Each year I would take all of Danu's copies of cerf forms, to the current eye specialist, that
the eye specialist used in the past years, to compare their findings. Each year, her
eyes never progessed beyond being suspicious, with also, her blood vessels
being normal. Pra always progresses. Pra does not lay dormant.
Danu is the 1st lowchen to be diagnosed with this new condition, Retinopathy, that is not a
form of pra. Nor does it appear to be hereditary, since the condition
has been going on for 8 years, with no changes.


CERF Liaison's discription of eye disorder.

Eye specialist write up

1. Bullae are blisters or small/focal retinal detachments. In different forms, degrees, etc., they characterize different retinal diseases. It sounds like your dog has some retinal lesions consistent with previous bullae or small detachments due to abnormal development or post inflammatory. These may have previously been interpreted or marked as suspicious for PRA but with more research and knowledge allowing changes to the CERF form, retinopathy (see below) which would describe/encompass such lesions, could now be described (or even marked/bubbled specifically on the most recent form which Dr. Weight used here) instead as this examiner did in her comments and the email to you.

2. Retinopathy just means pathology/disease or abnormality of the retina. PRA would be one form of retinopathy but not all retinal changes or retinopathies are PRA. In recent years in a number of breeds, retinopathy different from PRA but with other characteristics (often multiple bullous lesions but typically (not always) non-progressive and non-vision threatening) has become recognized and is now its own "bubble" on the CERF form and listed in the inherited disease book that we go by for these exams. Lowchens do not currently have this recognized as a known inherited eye disease (and the description in your dog is a little different than that in the dogs that do have this recognized but it may be yet another different form; it again also does not look like typical PRA....) and in your dog, retinopathy would pass and it would just be advised that you continue to monitor as you have been and also that we monitor the breed for others with this that might indicate inheritance..... I personally agree with this based on the description, time frame and unchanged lesions, that I would call your dog's lesions retinopathy and do not suspect they will progress to be a problem but they could and should still be monitored. They may or may not be inherited....the other Lowchen with a possibly similar non-progressive retinal change might actually indicate that this is an issue (though not really a problem for the individual dogs or breeding if it doesn't progress or cause visual issues....) but so far this is not recognized/known/published by ophthalmologists (with only two dogs and not necessarily the same type of retinal change....). That is the good thing about CERFs is that not only are they to help you for breeding, but we study these trends and may eventually be able to recognize a new disease (retinopathy in Lowchens) by collecting information from many CERFs...but again, for now, this is not recognized as an issue in this breed.

Finally, d2 in her notes is actually "dz" which is an abbreviation for disease - the note draws the location of the retinal change noted and says "doesn't look like an inherited disease"

I think it's fine to post this on your dog's health page and if people have questions, you can explain that these issues have been noted but are not causing him a problem though it may or may not be inherited.

Anyway, I know this is confusing and hope this helps somewhat. Please feel free to contact me with further questions or concerns.


Kathryn A. Diehl, DVM, MS, Diplomate, American College of Veterinary Ophthalmologists (ACVO) -ACVO CERF liaison -Former ACVO Genetics Committee Member (2007-2010) and Chair (2009-2010)


Message from the Examining Ophthalmologist.

From: Anne Weigt
Sent: Thursday, November 18, 2010 6:22 PM
Subject: your dog

I'm sorry, I don't remember your name -- but you came to the CERF clinic I did last Saturday in York, PA. Your dog had been examined for a number of years and from I could tell, the retina had not changed. It did not resemble a progressive disease, such as PRCD (progressive rod cone degeneration) also known as PRA. It looks more like an odd condition the dog was born with, or a previous bullae or detachment that sealed. Either way, I don't feel that your dog will go blind. I think he will continue to stay the same and keep the day and color vision that he has.

I hope this has answered your question, I was pressed for time that day. Please feel free to email me back if I did not answer it fully.

Dr. Anne Weigt
Animal Eye Care

Please see Canine Eye Registration Foundation form, that eye specialist use, (Danu's 2010 cerf form). Report can be printed out Click here

How to read a Cerf Certificate.Click here

View Danu's Ophthalmic Examination Form 2004. Report can be printed out. Click here

BAER Locations
Brainstem Auditory Evoked Response (BAER) hearing testing

Optigen   Testing for prcd mutation test for pra.

Orthopedic Foundation for Animals  Testing of hips.

CERF   Cerf is another eye test, that is to be done on a "yearly" basis.
To rule out any other ocular disorders, of just not the Lowchen
breed, but of "all" breeds. This test should be done though out
the life time of the Lowchen breed, and all breeds, especially
when used in a breeding program

*NEW -- Cerf Statistics Report For Eye Diseases In The Lowchen Breed. More to come!
(Reports can be printed out)

2008] 2009] 2010] 2011] 2012]

Listed are examples of ocular disorders that occur in some breeds.
Not all breeds carry the same eye disorders. These are only examples, of
some of the ocular disorders, of what cerf checks for.


  • Cataracts
  • Glaucoma
  • Microphthalmia
  • Entropion
  • Distichiasis
  • Dry Eye
  • PRA



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My Lowchens ERG'd on March 31, 1993, at Cornell University, New York

LCA-ROM Kismet's Popcorn Of Rygate(Popcorn) DOB 12/10/1988
LCA Ch. Marcel Golden Gamin ex LCA Ch. Destinys Lady Tache LCA-ROM

LCA Ch. Lionheart Be-Bop-A-Lula(Lula) DOB 12/01/1990
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LCA Ch. Destiny's Mistique of Rygate(Tiffany) DOB 8/13/1989
Destiny's Strike Up The Band ex LCA Ch. Destiny's Definitely

LCA Ch. Rygates Poppin Fresh(Gabby) DOB 3/6/91
LCA-ROM Kismet's Popcorn of Rygate ex LCA Ch. Destiny's Mistique Of Rygate


*NEW -- Cerf Statistics Report For Eye Diseases In The Lowchen Breed. More to come!
(Reports can be printed out)

2008] 2009] 2010] 2011] 2012]

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